At treatment appointment it is necessary to distinguish sporadic and рецидивирующие disease episodes. Not complicated споррадические cases usually are caused штаммами C albicans. The majority of these штаммов is sensitive to противогрибковым to preparations on a basis азола. As a whole, it is noted special distinction in activity in vitro and clinical efficiency various азоловых the preparations applied местно. Thus, the practical doctor can begin treatment empirically without культурального crops. In not complicated cases the treatment choice is usually based on preferences of the patient. For treatment вульвовагинального a candidiasis there are many the various schemes of treatment including use both oral, and local preparations. At oral reception of a preparation it is necessary to consider possibility of its interaction with other medicines. Гепатотоксичность, connected with reception кетоконазола, meets approximately in 1 case from 10,000-15,000. Флюконозол is less toxic, than кетоконазол. By-effects include also a nausea, a pain in a stomach, headaches. Interactions meet other medicines at simultaneous reception блокаторов кальциевых channels, варфарина, циклоспорина, oral сахароснежающих preparations, ингибиторов протеаз, теофиллина, rifampicin.